Product Name :
PAG1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
CBP Csk Binding Protein Csk-binding protein FLJ37858 MGC138364 PAG 1 PAG PAG1 PAG1_HUMAN Phosphoprotein associated with glycosphingolipid enriched microdomains 1 展开
Function :
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human PAG1 331-432/432
Species reactivity:
Human, Mouse, Rat, Dog, Horse, Rabbit
Verify application:
WB, ELISA, IHC-P, IF, ICC
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.Price of Sodium difluoromethanesulfinate Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.Formula of 5-Bromo-1H-pyrazole-3-carboxylic acid
Storage buffer solution:
0.PMID:33606350 01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
47 KDa
Positive control :
Ubiquitously expressed. Present in germinal center B-cells, plasma cells, T-cells, monocytes and platelets (at protein level).