Product Name :
PDIA6 Recombinant Rabbit Monoclonal Antibody [JF0974]
Predicted band size :
Observed band size :
Synonyms:
Endoplasmic reticulum protein 5 antibody ER protein 5 antibody ERp5 antibody P5 antibody Pdia6 antibody PDIA6_HUMAN antibody Protein disulfide isomerase A6 antibody Protein disulfide isomerase associated 6 antibody Protein disulfide isomerase family A member 6 antibody Protein disulfide isomerase P5 antibody 展开
Function :
Endoplasmic reticulum proteins (ERps) are widely expressed proteins that localize to the ER and may act as proteases, protein disulfide isomerases, thiol-disulfide oxidases or phospholipases. ERp5, also known as PDIA6 (protein disulfide isomerase family A, member 6) or TXNDC7 is a 440 amino acid protein that contains two thioredoxin domains and belongs to the protein disulfide isomerase family. Localized to the melanosome, as well as to the lumen of the endoplasmic reticulum, ERp5 functions to catalyze the rearrangement of disulfide bonds in a variety of different proteins. Via its catalytic activity, ERp5 is able to reduce the disulfide bond that binds MICA to tumor cells, thereby releasing MICA and reducing the rate of tumor expansion. Multiple isoforms of ERp5 exist due to alternative splicing events.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within PDIA6 aa 1-108 / 440.Formula of (S)-(+)-Norepinephrine L-bitartrate
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, FC
Coupling :
unconjugated
Clone number:
JF0974
RRID:
AB_3070289
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Price of 1210834-55-1 Aliquot store at -20℃ or -80℃.PMID:33522434 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
48 kDa
Positive control :
HepG2 cell lysate, K562 cell lysate, Hela, HepG2, NIH/3T3.