Product Name :
2-Furoyl-LIGRLO-amide trifluoroacetate salt (CAS 729589-58-6 (non-salt))
Synonym :
2-Furoyl-Leu-Ile-Gly-Arg-Leu-Orn-NH2 trifluoroacetate salt; 2-fAP; 2-Fly
Application :
2-Furoyl-LIGRLO-amide trifluoroacetate salt is a potent, selective PAR2 agonist
CAS:
729589-58-6 (non-salt)
Purity:
Molecular Weight:
777.95 (free base)
Formula :
C36H63N11O8•xC2HF3O2
Physical state:
Solid
solubility :
Soluble in water (>2 mg/ml).
Shipping Condition :
Store at -20° C
Melting point:
SMILES:
References:
:PAR2 regulates regeneration, transdifferentiation, and death. | Piran, R., et al. 2016. Cell Death Dis. 7: e2452. PMID: 27809303Disrupting sensitization of TRPV4. | Mack, K. and Fischer, MJM. 2017. Neuroscience. 352: 1-8. PMID: 28372987Tryptase promotes breast cancer angiogenesis through PAR-2 mediated endothelial progenitor cell activation.1-Methylcyclopropanamine hydrochloride uses | Qian, N., et al.Formula of 250674-51-2 2018.PMID:33560694 Oncol Lett. 16: 1513-1520. PMID: 30008831PAR2 promotes M1 macrophage polarization and inflammation via FOXO1 pathway. | Chen, L., et al. 2019. J Cell Biochem. 120: 9799-9809. PMID: 30552714Macrophage TLR4 and PAR2 Signaling: Role in Regulating Vascular Inflammatory Injury and Repair. | Rayees, S., et al. 2020. Front Immunol. 11: 2091. PMID: 33072072